Signal Transduction

Signal Transduction, 2e Bastien D. GompertsUniversity College, London, United KingdomIjsbrand M. KramerUniversity of Bordeaux, Talence, FrancePeter E.R. TathamUniversity College, London, United KingdomMiranda Gomperts KEY * Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention* In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and intracellular calcium* Extensive conceptual colour artwork to assist with comprehension of key topics * Instrumental margin notes highlight milestones in signalling mechanisms Signal Transduction is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. RELATED EUKARYOTIC TRANSCRIPTION FACTORS, 3E (1998; 0-12-437176-0; $62.95) . In-depth insight into a subject central to cell biology and fundamental to biomedicine, including drug development. Extensive conceptual colour artwork to assist with comprehension of key topics. Special emphasis on the integration of how molecular (domain) structure determines protein function. Comprehensive referencing of both core and historical literature. Guided access and inclusion of Protein Data Bank and Swiss-Prot accession codes and URLs