Bipolar Depression: A Comprehensive Guide

Although depression is the most common presentation of bipolar disorder, correct diagnosis presents a formidable challenge. Bipolar Depression introduces a model for diagnosis that allows the clinician to distinguish between bipolar and unipolar depression, addressing problems of misdiagnosis and overdiagnosis, as well as differentiate attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder. The contributors first review neurobiology and genetics, bipolar depression in children, and considerations regarding suicide, then offer critiques of specific treatment approaches.This valuable volume focuses on the use of lithium and antiepileptic drugs, featuring a review of the most recent research on the former, for which higher doses are shown to be effective; antidepressants, offering a discussion of the randomized clinical trial literature and observational studies; and antipsychotics, evaluating the difference between first- and second-generation medications. Other chapters assess novel approaches to treatment such as atypical neuroleptics, electroconvulsive therapy, transcranial magnetic stimulation, and ketogenic diet; as well as psychological interventions, focusing on the inclusion of cognitive-behavioral therapy or interpersonal social rhythm therapy. Together, these chapters constitute a summary of the most recent research that opens new doors in recognizing differences between bipolar and unipolar forms of depression while offering key insights into the management of this illness.