RUNX Proteins in Development and Cancer

RUNX Proteins in Development and Cancer

Yoram Groner , Yoshiaki Ito , Paul Liu
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Mar 23, 2017 · English · Hardcover (535 pages)
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Book Details

Format Hardcover
Pages 535
Language English
Published Mar 23, 2017
Publisher Springer
ISBN-10 9811032319
ISBN-13 9789811032318

Description

RUNX proteins play a vital role in various biological processes, making their study essential for understanding both developmental biology and cancer. This comprehensive volume delves into the multifaceted roles of RUNX proteins, unraveling their significance in regulating gene expression, cell differentiation, and maturation. Readers will find insights into the evolutionary conservation of these proteins, as well as their involvement in both normal and pathological biological contexts.

Contributions from a team of distinguished authors illuminate the complex interplay between RUNX proteins and critical signaling pathways. The text highlights how mutations or dysregulation of these genes can lead to a range of malignancies, offering a bridge between molecular biology and clinical implications. Each chapter serves to enhance the reader's comprehension of the mechanisms underlying RUNX expression and its impact on health and disease.

The volume is not only an essential resource for researchers and clinicians but also provides a basis for further studies aimed at therapeutic interventions. By examining the latest findings and ongoing research, readers can appreciate the potential of RUNX proteins as biomarkers and therapeutic targets, paving the way for future innovations in cancer treatment and developmental therapies.

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